The military exchanges worsened between Israel and Iran overnight on Monday as strikes hit residential areas, killing and wounding civilians on both sides.

The Iran regime is very weak,” Israeli Prime Minister Benjamin Netanyahu said in a television interview. Israeli struck energy facilities and government buildings Sunday.

Iranian news media and residents of Tehran say the damage from the latest Israeli strikes appears to be significant, with several apartment buildings badly damaged. Residents say they are hearing ambulance sirens and fire trucks racing to the scenes and rescue workers are working to find casualties in the rubble.

A new explosion was heard at a key uranium enrichment site in central Iran on Friday morning, hours after Israel launched unprecedented air strikes against the Islamic Republic's nuclear programme.