In the second round of the NBA Draft, two former Blue Devil guards were selected. 3-and-D specialist Sion James will join his former teammate, Knueppel, in Charlotte. The last Blue Devil draft pick in 2025 was Tyrese Proctor. The sharpshooter was picked 49th by the Cleveland Cavaliers.

Duke saw its entire starting 5 drafted in the 2025 NBA Draft, joining some elite company in the history of the NBA.

The SEC rode a strong second round to the top of the charts in the 2025 NBA Draft, as the conference finished with 13 total selections. Eight of 29 players selected on Thursday night came from the league, which was in second place behind the Big Ten after Wednesday's first round.