U.S. stocks were headed for slight losses early on Wednesday after strong gains the previous day over easing trade tensions with the European Union. Earnings from chip maker Nvidia after the market close are set to take the spotlight.

Fears have grown that a new U.S. budget bill would put even more stress on the country’s already large deficit.

Futures for Canada's main stock index edged lower on Wednesday, pulling back from the previous session's record high, as investors awaited trade-related developments and chip giant Nvidia's quarterly results later in the day.

Good morning from London. It's just over 90 minutes until European equity markets open, after which stocks look set to trade in mixed territory. Futures tied to the German DAX index are currently down 0.2% and FTSE 100 futures are marginally lower. French CAC 40 futures are bucking the trend with a 0.2% rise.

S&P 500 futures are dipping 0.1%. Dow Jones Industrial Average futures are down 0.2%. Nasdaq 100 futures are slipping 0.1%. On Tuesday, the Dow Jones Industrial Average rose 741 points, or 1.78%, to 42,

Oil futures settle lower for a second straight session after a rally on a report that Israel may be preparing to attack Iran's nuclear facilities fizzled out. Market focus turned to fundamentals as the EIA reported a second straight weekly build in U.