Amyloid precursor protein (APP) is a type I transmembrane glycoprotein that undergoes complex routing through the secretory and endocytic pathways of neurons and non-neuronal cells. Proteolytic ...
Selective serotonin reuptake inhibitors (SSRIs) target serotonin receptor transporters (SERT), preventing serotonin re-uptake from the synapse. The use of SSRIs may modify some disease process via ...
Researchers at Niigata University's Brain Research Institute have uncovered a new function of amyloid precursor protein (APP) ...
Brain cells are constantly swallowing material from the fluid that surrounds them—signaling molecules, nutrients, even pieces of their own surfaces—in a process known as endocytosis that is essential ...
Share on Pinterest New research looks into the role of amyloid-beta in developing Alzheimer’s. Westend61/Getty Images A main theory behind the cause of Alzheimer’s disease is the build-up of the ...
(A, B) ALP staining and activity detection were performed after treating cells with APPswe or BMP2 for 5 days or 7 days. (C, D) ARS staining and semiquantitative analysis were used to detect calcium ...
Cerebral amyloid angiopathy is a major cause of hemorrhagic stroke, a frequent contributor to age-related cognitive impairment, and a key component in adverse responses to beta-amyloid (Aβ) ...
At the end of last month, a scientific journal pulled a research paper on Alzheimer’s disease. The retraction came from Neurobiology of Aging, which removed a 2011 paper claiming to show that a ...
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