A preclinical CRISPR screen found that loss of mTOR-regulating genes sensitizes small cell lung cancer cells to PARP ...
A genome-wide CRISPR screen identifies UGCG-driven sphingolipid metabolism and protective autophagy as drivers of Niraparib ...
Bollywood actor and cancer survivor Sonali Bendre shared a post crediting autophagy as part of her healing journey. But the response she got was far from unanimous admiration. The 50-year-old actor, ...
Autophagy is a critical cellular process that removes damaged organelles and recycles nutrients to maintain homeostasis. In cancer, autophagy plays a complex role, supporting tumor suppression and ...
A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...
Autophagy of cancer cells has been frequently observed during radiotherapy. In addition, pancreatic cancer-associated fibroblasts can compromise the radiotherapeutic effect by promoting the autophagy ...
Our bodies are made up of billions of cells. Each cell is a tiny world of its own, where molecules are continuously produced, ...
Illustration of an autophagosome (light blue double-membrane to the right) engulfing cellular material. David S. Goodsell and Daniel Klionsky/RCSB PDB-101, CC BY-SA Don’t let the textbook diagram of a ...
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