The mechanisms that control cell growth during the cell cycle are poorly understood. In budding yeast, cyclin dependent kinase 1 (Cdk1) triggers polarization of the actin cytoskeleton and bud ...
Maskin regulates assembly of the eIF4F translation initiation complex on messenger RNAs that contain cytoplasmic polyadenylation elements (CPEs) in their 3′ untranslated regions. Because Maskin and ...
Somatic mammalian cells possess well-established S-phase programs with specific regions of the genome replicated at precise times. The ATR-Chk1 pathway plays a central role in these programs, but the ...
Discovery of a molecule that initiates maturation of mammalian eggs can lead to more IVF pregnancies
Women who have eggs that cannot mature will not become pregnant, and they cannot be helped by in vitro fertilization (IVF). Now researchers have identified a molecule called Cdk1 that has an important ...
Women whose egg cells do not mature will not become pregnant, and they cannot be helped by in vitro fertilization (IVF), which requires mature egg cells to produce an embryo. Now, researchers in ...
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