Week 10 of the 2025 college football season kicks into full swing on Saturday afternoon with a great slate of games loaded with marquee matchups across the nation. Saturday’s schedule includes three ranked vs.

Iowa State Cyclones vs ASU Sun Devils picks, predictions, odds, probabilities for college football Week 10 Saturday game Nov. 1. Who will win today?

The College Football Playoff selection committee will release its first set of rankings Tuesday but not before teams jostle for position Saturday.

The Buckeyes had a Week 9 bye and remain the No. 1 team in the US LBM coaches poll with a 7-0 record. Ohio State's defense has allowed 5.8 points per game, the fewest in the FBS and the lowest average through seven games in the FBS since 1993.

South Carolina fans have hit a boiling point after Saturday's loss, calling for the program to make a change at head coach across social media. "Shane Beamer needs to be fired for simply continuing to allow Mike Shula to call plays," one fan said.

Major changes in our bowl projections exiting Week 10 ahead of the selection committee's first rankings release

No. 12 Notre Dame travels to Chestnut Hill to take on Boston College at Alumni Stadium (3:30 p.m. ET, ESPN) on Saturday, and the Fighting Irish are looking to continue their ascent up the rankings with a sixth straight win.

The No. 23 USC Trojans (5-1, 3-1 Big Ten) are back on the road after having its second bye week. They travel to Lincoln to face the Nebraska Cornhuskers (6-2, 3

The No. 7 Yellow Jackets (8-1, 5-1 ACC) also are no longer in first place in the ACC standings after the loss, falling behind No. 15 Virginia (8-1, 5-0), who defeated California 31-21 to move to 5-0 in conference play this season.