A so-called "molecular chaperone", the protein Hsp70, carries out more functions in the maturation of proteins than previously thought. As the researchers have discovered, Hsp70 not only acts as a ...

Using a combination of computational and experimental techniques, a research team at the University of Massachusetts Amherst led by molecular biologist Lila Gierasch has demystified the pathway of ...

Heat shock protein 70 chaperones exert neuroprotective effects by preventing aggregation and regulating the proteostasis of pathological protein via its degradation. Neurodegenerative diseases such as ...