The fragments also directly compromise synapses they encounter along the way, according to a preprint posted February 24 on bioRxiv. Specifically, tau fragments containing the microtubule binding ...

Two major forms of synaptic plasticity, long-term potentiation (LTP) and long-term depression (LTD) are cellular processes involved in learning and memory. Although they produce opposite effects ...

In 1949, Donald Hebb predicted a form of synaptic plasticity driven by temporal ... was verified decades later with the discovery of long-term potentiation, securing Hebb's place in the scientific ...

which help create nitric oxide the brain needs for synaptic plasticity and long-term potentiation. Published in the journal PNAS Nexus, Anni Vanhatalo and colleagues characterized the oral ...