A new study in PLOS Biology shows that the nuclear hormone receptor NHR-68 links intestinal linoleic acid metabolism to both ...
Researchers show that the ligand-independent nuclear receptor BmERR uses its AF-2 domain to recruit the coactivator PPRC1 and ...
Chinese Medical Journals Publishing House Co., Ltd. Brain cancer is one of the most aggressive and life-threatening diseases, with glioblastoma (GBM) being the most common and deadliest type. Patients ...
A new scientific review has revealed crucial insights into how two types of hormone receptors collaborate to protect brain health and potentially prevent neurodegenerative diseases. The study, ...
(MEMPHIS, Tenn. – November 6, 2025) A study from St. Jude Children’s Research Hospital uncovered an alternative binding pocket within nuclear receptors, revealing a much-needed new therapy route for ...
A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, revealing a much-needed new therapy route for this important class of drug targets.
Researchers confirm and explore the role of estrogen-related receptors in regulating energy production in muscle cells during exercise. The findings indicate that developing a drug to boost ...
Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time, uncovering how it functions, which may enable better ...