(A) Schematic of the splicing reporter minigene used in transient transfection assays and the different mRNA isoforms derived from it. (B) RT-PCR analysis of minigene-derived extra domain A (EDA) EDA+ ...
To discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and (pre)clinical data with new PI 3-kinase ...
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