In other subtypes of glioblastomas, Stat3 functions as a tumor suppressor gene. In the tissue samples above, the cancer has lost the tumor-suppressor PTEN, leaving that function almost entirely up to ...

VVD-130850 is an investigational oral small molecule inhibitor of STAT3 transcription factor developed for treatment of advanced solid and hematologic tumors as a single agent and in combination with ...

March 25, 2013--TAMPA, Fla. – Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have developed a small molecule that inhibits STAT3, a protein that causes cancer.

New Haven, Conn. -- Protein molecules that help maintain a healthy body temperature, electrolyte balance, respiration, heart rate, and other critical functions, also appear to regulate weight and ...