Our cells produce a variety of proteins, each with a specific role that, in many cases, means that they need to be in a particular part of the cell where that role is needed. One of the ways that ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

The maps of electrical brain activity taken during the making of memories are well established, but how those memories are stored and subsequently released remains unclear. In 23 October Proceedings ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

A new study by researchers at Kiel University and MPI-EvolBio describes how more efficient protein production drives the adaptation of fungi to the human body, potentially turning previously harmless ...

A GGGGCC hexanucleotide repeat expansion in intron 1 of the C9ORF72 gene causes familial amyotrophic lateral sclerosis and frontotemporal dementia. Aberrant translation of this expansion results in ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 51 (December 19, 2017), pp. 13424-13429 (6 pages) Unlike most macromolecules that are homogeneously ...

Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

MIT’s Markus Buehler specializes in developing AI models to design new proteins and is perhaps best known for using sonification to illuminate structural details that might otherwise prove elusive.