JA Rosenfeld is an employee of Signature Genomic Laboratories, a subsidiary of PerkinElmer, Inc. The authors have no other relevant affiliations or financial involvement with any organization or ...
Impact of BRCA1 gene alterations on tumor characteristics and clinical outcome in ovarian cancer (OC) patients. Background: Advanced ovarian clear cell carcinomas (OCCCs) are notoriously drug ...
Analysis of histological sections of disease tissues has traditionally relied on pathologist-based scoring. In an Advanced Online Publication in Nature Medicine Camp et al. describe techniques to ...
Use of SUVmax to predict response to neoadjuvant chemoradiotherapy in patients with adenocarcinoma of the distal esophagus and GE Junction ...
Chromosomal microarray analysis (CMA) has been recommended and practiced routinely since 2010 both in the USA and Europe as the first-tier cytogenetic test for patients with unexplained ...
The first study of the use of microarray patches to vaccinate children has shown that the method is safe and induces strong immune responses. The phase 1/2 randomized trial compared results from the ...
The human genome project was undertaken to determine the human DNA sequence and analyze variation among individuals. To make use of this information, tools were developed that could collect and ...
To evaluate if the NT value of 2.5 mm ≤ NT < 3.0 mm is an appropriate indication for CMA tests among fetuses with isolated increased NT and NIPT is more suitable instead. A total of 442 fetuses with ...
Launched in 1990, The Human Genome Project was a monumental effort to sequence and analyze the entire human genome to understand how genetics influence health. While the Human Genome Project helped ...
The Geniom® RT Analyzer, a new benchtop microarray processing instrument, was presented by febit at Select Bioscience’s “Advances in Microarray Technology”. The platform complements Geniom® One, the ...
Protein microarrays are many things to many people. Like the more mature DNA “chips”, they are often patterns of tiny spots arrayed on a microscope-type slide, used to determine the makeup and amount ...
The research community's rapid acceptance of microarrays notwithstanding, technical challenges remain. Biochip developers continue to grapple with these issues while upgrading their offerings and ...