Instrument Seeks to Advance Ligand-Gated Aspect of Critically Important Field The first decade of the 21st century has delivered an extraordinary range of new technologies with relevance to ...

The study from St. Jude Children's Research Hospital presents a new understanding of how a VGIC, crucial for the communication of neurons and muscle cells, can become unresponsive. Scientists at St.

Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed ...

Maintenance of cardiac rhythm and pain sensation require the flow of ions across the membranes of all cells. Ion channels, which facilitate this movement, are protein assemblies that penetrate the ...

In a recent study posted to the bioRxiv* preprint server, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium ...

Historically, researchers impaled giant squid, snail, and frog axons with electrodes to study nerve function by measuring ion channels. Today, electrophysiologists have enhanced their ability to ...

When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical ...

CAMBRIDGE, England & BRUSSELS--(BUSINESS WIRE)--Metrion Biosciences Limited (“Metrion”), the specialist ion channel contract research and drug discovery company, and Bioqube Ventures (“Bioqube”), a ...

image: From left to right, Dr. Chia-Hsueh Lee and Dr. Hongtu Zhao of the Department of Structural Biology at St. Jude Children's Research Hospital. Dr. Lee and Dr. Zhao are co-authors of a new study ...

The EIT–EVA PCB sensor setup used to evaluate the effects of drugs on hERG channels. The sensor measures changes in extracellular resistance as voltage-gated hERG channels are activated and inhibited, ...