BALTIMORE--(BUSINESS WIRE)--Cerecor Inc. (NASDAQ: CERC), a clinical-stage biopharmaceutical company developing treatments to make a difference in the lives of patients with neurological and ...

Information processing in the brain is thought to exploit not only classical homosynaptic connections between pre- and postsynaptic neurons but also heterosynaptic interactions between separate ...

Glutamate, the major excitatory neurotransmitter in the brain, acts primarily on two types of ionotropic receptors: α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors and N-methyl-D ...

Researchers have shown in animal studies how receptors on nerve cells can become altered to produce chronic pain triggered by inflammation. They say that their findings could aid in developing new ...

The AMPA receptors are embedded in the cell membrane but quite mobile and can add to or take away from the synapse by moving in or out of it, she said. "The idea is that when a synapse experiences ...

Behind every successful neuron, and some unsuccessful ones, there are astrocytes. These accessory cells nurture and protect their finicky neighbors by providing nutrients, neurotrophic factors, and ...

One of the earliest signs of amyloid-β (Aβ) toxicity is synaptic loss, and recent work from a number of labs has shown that Aβ causes depressed synaptic transmission due to removal of cell surface ...

While the COVID pandemic has thankfully been over for some time now, there is still a considerable number of people in the world (about 400 million) suffering from long COVID. Long COVID is a chronic ...

Brief forebrain ischemia in rodents induces selective and delayed neuronal death, particularly of hippocampal CA1 pyramidal neurons. Neuronal death is preceded by down-regulation specific to CA1 of ...

A University of Central Florida researcher has discovered that altering a receptor that mediates communication between nerve cells in the brain significantly improves animals' chances of surviving ...