Randomized trials also provide investigators with a platform to prospectively study patient-reported outcomes and quality of life as well as to collect economic data for cost-effectiveness analyses ...

This review article considers the strengths and weaknesses of randomized clinical trials that are conducted through the analysis of data gathered by health insurers.

The purpose of our review is to determine how useful randomized controlled trials (RCTs) in the WWC might be in helping teachers and school administrators make accurate, informed decisions about ...

Methods In this randomized, controlled trial, we enrolled 100 patients with moderate-to-severe knee osteoarthritis who were eligible for unilateral total knee replacement.

Because of ethical considerations, scientists haven’t been able to conduct randomized controlled trials to conclusively prove the effectiveness of mask-wearing on interrupting coronavirus ...

Introduction Many people with psychosis find the world very frightening. It can be difficult for them to do everyday things—for example, walking down a busy street, travelling on a bus or going to the ...

Relevant trial designs that have been developed and utilized include phase II selection designs, randomized phase II designs that include a reference standard-treatment control arm, and phase II/III ...

One way to avoid these confounds could be a randomized controlled trial (RCT) that divides people into otherwise equivalent groups that either do or do not receive an intended treatment.