Xiaflex was approved in 2010 for the treatment of Dupuytren’s contracture. Dupuytren’s contracture is a condition where nodules form under the skin in the palm of the hand. These nodules thicken and ...

If you have Dupuytren's contracture, you're likely familiar with the many nonsurgical ways to manage the condition, including hand exercises, physical therapy, and injections. While these treatments ...

Dupuytren’s contracture is a condition that causes tissue beneath the skin of your palm (fascia) to thicken and form tough bands called cords. These cords tighten and gradually pull one or more ...

The genetic disorder affects the palmar fascia, the thick layer of tissue found in the palm of the hand. Treatment is dependent on an individual’s symptoms and quality of life. Dupuytren’s disease is ...

Treatments for Dupuytren’s contracture include limited fasciectomy and collagenase injection. Comparisons of the effectiveness of these treatments have been limited. We performed an unblinded, ...