While our understanding of Alzheimer’s disease is far from complete, the latest therapies, and others in more than 100 clinical trials, offer new hope

Alzheimer’s disease has proved to be a tricky target, and researchers and drug developers have been pursuing effective treatments for decades. The brains of people who die with Alzheimer’s show a distinct biology: clumps or “plaques” of amyloid beta proteins in spaces between neurons and tangles of tau proteins that accumulate primarily within the nerve cells.