The U.S. military is operating in the air, on land and at sea to shoot down Iranian missiles fired at Israel.

Israel launched “preemptive” strikes early Friday across Iran, amid growing regional tensions and concerns about Iran’s nuclear capabilities.

The Israeli military has warned that “all of Israel is under fire” after Iran launched retaliatory strikes on Friday, following Israel’s attacks on Iranian military and nuclear targets.

Iran's Islamic Revolution Guards Corps (IRGC) launched late Saturday night a "large-scale combined offensive operation" against Israel, involving a significant number of missiles and drones, the IRGC's official news outlet Sepah News reported.

Iranian media say Israeli attacks have killed at least 80 people and wounded 800 others over the past two days. Those killed include 20 children

Sirens sounded in Israel as Iran launched dozens of ballistic missiles in retaliation for Israel's strikes on its nuclear facilities.

Israel’s ongoing attacks on Iranian nuclear sites killed 78 people and wounded more that 320 on Friday, said Iran’s ambassador to the United Nations. The strikes killed generals and scientists, but the ambassador told the U.N. Security Council that “the overwhelming majority” of victims were civilians.

Iran is planning to 'give a harsh response' to an Israeli attack launched early on Friday against its nuclear programme, an Iranian security source told Reuters.

Iran launched retaliatory strikes on Israel after Netanyahu said Israel began an operation to push back on Iran's "threat to Israel's very survival."

In all, at least 20 senior commanders were killed, two regional sources said. The head of the Revolutionary Guards aerospace force was also reported to be among them.