TEL AVIV, Israel (AP) — Iran fired a new wave of missile attacks on Israel early Monday, killing at least five people, while Israel claimed in the fourth day of the conflict that it had now achieved “aerial superiority” over Tehran and could fly over the Iranian capital without facing major threats.

Israel has launched a series of strikes against Iran, targeting the country’s nuclear program and other military infrastructure. Iran has launched its own strikes in retaliation.

Israel's conflict with Iran represents far more than another Middle Eastern crisis—it marks the emergence of a dangerous new chapter in nuclear rivalries that has the potential to reshape global proliferation risks for decades to come.

Since Israel began its concerted attack on Iran on Friday, calls for regime change in Iran have grown louder – from hawks in the US Congress to Israeli officials and some Iranian activists abroad.

"The military standoff needs to stop in order to stabilize the situation," Deputy Foreign Minister Sergey Ryabko said.