Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

As we look ahead in 2025, the pace of discovery in genetics continues to accelerate, marking the third decade of the 21st century with remarkable ...

Research from UChicago dissects how a single genetic switch helps butterflies mimic wing patterns of other species to protect ...

This study presents valuable findings on the role of KLF6 in in vitro endothelial cells exposed to altered (high or low) shear stress with a customized microfluidic device to investigate mechanisms of ...

A top US regulator plans to unveil a faster approach to approving custom gene-editing treatments, a move designed to unleash a wave of industry investment that will yield cures for patients with rare ...

Peptides derived from endogenous regulatory proteins are believed to often serve as intriguing molecular probes in neuroscience and related fields.

This important study examines the potential role of ARHGAP36 transcriptional regulation by FOXC1 in controlling sonic hedgehog signaling in human neuroblastoma. While there are many solid findings ...

The most dangerous animal in the world just got easier to study—and perhaps defeat one day.Researchers from Rockefeller University's Laboratory of ...

Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE) today announced that the first patient has been dosed in the Aurora study (NCT07157254) evaluating the efficacy and safety of GTX-102 (apazunersen), an ...

Selective autophagy ensures the targeted degradation of damaged or surplus cellular components, including organelles, thereby ...