Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...
As we look ahead in 2025, the pace of discovery in genetics continues to accelerate, marking the third decade of the 21st century with remarkable ...
The manuscript concerns a fundamental and controversial question in Trypanosoma brucei biology and the parasite life cycle, providing further evidence that slender bloodstream forms can indeed infect ...
Peptides derived from endogenous regulatory proteins are believed to often serve as intriguing molecular probes in neuroscience and related fields.
The most dangerous animal in the world just got easier to study—and perhaps defeat one day.Researchers from Rockefeller University's Laboratory of ...
Acute lung injury (ALI) is a critical clinical condition characterized by diffuse inflammation of the lung parenchyma and ...
Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE) today announced that the first patient has been dosed in the Aurora study (NCT07157254) evaluating the efficacy and safety of GTX-102 (apazunersen), an ...
Selective autophagy ensures the targeted degradation of damaged or surplus cellular components, including organelles, thereby ...
Type 1 diabetes (T1D) is a chronic autoimmune disease that results from the destruction of insulin-producing β-cells in the ...
Researchers have shown for the first time that flipping an epigenetic “switch” in specific memory-holding neurons can directly alter memory strength.
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