Erythroid cell patterns in neoplasms show distinct genomic profile and poor venetoclax response, new research suggests.

Updated data from the BEXMAB study reveals a significant increase in complete remission rates for patients with high-risk ...

One patient assigned to ibrutinib-venetoclax developed myelodysplastic syndrome / acute myeloid leukemia (AML), as did eight patients assigned to FCR.

The study evaluated a combination therapy involving its blockbuster cancer drug Venclexta (venetoclax) in newly diagnosed patients with higher-risk myelodysplastic syndrome (MDS).

And I think we'll get into, you know, the probably greatest unmet need is, once we do fail HMA-based therapy, particularly for higher risk myelodysplastic syndrome patients, there's really nothing.

AbbVie said its Phase 3 trial evaluating venetoclax in combination with azacitidine to treat higher-risk myelodysplastic syndrome didn't meet the primary endpoint of overall survival.

Myelodysplastic syndrome is a rare blood cancer that occurs when the DNA in bone marrow stem cells is damaged, preventing them from producing healthy blood cells. In the first 190 enrolled ...

Phase 1b/2 Study of Lisaftoclax (APG-2575) Combined with Azacitidine (AZA) in Patients with Treatment-Naïve or Prior Venetoclax-Exposed Myeloid Malignancies Abstract #: 6505 Format: Oral Presentation ...

And this was in all-comer, lower-risk, myelodysplastic syndrome. So, we anticipate that there will be a label change, in the near future, supporting a frontline treatment option.

Key myelodysplastic syndrome pipeline therapies in various stages of development include MBG453, Tamibarotene, CA-4948, RVU120, TQB2618, AMG 176, SAR443579, Etavopivat, AG-946, Venetoclax ...

Shorter venetoclax durations in patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) yielded comparable survival outcomes in a new study, challenging treatment norms ...