NFL Week 6 picks, predictions for games this week, including 49ers-Seahawks, Commanders-Ravens, Buccaneers-Saints, ...

Cleveland Browns quarterback Deshaun Watson completed 15-of-28 passes fo 125 yards in a blowout 34-13 loss to the Washington ...

A marathon Sunday of Week 5 produced plenty of winners and losers, with the 49ers and Bills among the teams sparking concerns ...

Tom Brady reminisced on facing San Francisco 49ers quarterback Brock Purdy in 2022, the final season of his career.

Here’s what fans and analysts were saying on Twitter after the 49ers dropped a shocking loss to the Cardinals in Week 5.

San Francisco 49ers running back Christian McCaffrey could make his season debut during Week 7 against the Kansas City Chiefs ...

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

Half of the 10 Sunday afternoon games on the Week 5 NFL schedule are divisional matchups, but oddly, none of them features a ...

It was a good day for the future of the Las Vegas Raiders. Not because of what happened in their matchup against the Denver ...

Why San Francisco 49ers changed their uniform for NFL Week 5 game against Arizona Cardinals Sunday, and why it's not the ...

What to look for from the top 49ers and Cardinals players and how to watch the game as they face off on Sunday, week 5.

The Arizona Cardinals and San Francisco 49ers will kick off Sunday afternoon from Levi's Stadium at 1:05 p.m. Arizona time.