The researchers reported that they have already discovered novel functions for two epilepsy drugs previously not known to act on GABA A receptors. "This research helps explain how the brain's ...

The researchers reported that they have already discovered novel functions for two epilepsy drugs previously not known to act on GABA A receptors. "This research helps explain how the brain's ...

So-called GABA A receptors are proteins that control the flow of ions into and out of cells. As they play such a vital role in how neurons slow down or stop firing, they have become the targets of ...

Vagus Nerve Stimulation therapy is a treatment for epilepsy that involves a stimulator (or 'pulse generator') which is connected, inside the body, to the left vagus nerve in the neck. The stimulator ...

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Nonuniform organization of channels and NMDA receptors in L2/3 dendrites could serve to independently modulate these information streams to affect learning and behavior, yet whether L2/3 PC dendrites ...

Analyses of large databases have provided clarity on the lived experiences of people with epilepsy regarding the initiation of or changes to their antiseizure medications. The past year has also seen ...

A variety of additional clinicopathological variables were considered, including menopausal status at diagnosis, body mass index, hormonal receptor status (estrogen and progesterone, positive or ...

RAP-219 is a clinical-stage AMPA receptor negative allosteric modulator, designed to treat focal epilepsy and other CNS disorders. What were the results of the PET and MAD-2 trials for RAP-219?

Additionally, the data provide further support for the dosing regimen selected for our ongoing Phase 2a trial in focal epilepsy ... evidence of selectively targeting TARPγ8 associated AMPA receptors ...

AMPA receptors are present throughout the brain ... as a potentially differentiated treatment for patients with focal epilepsy, diabetic peripheral neuropathic pain, and bipolar mania.