Textbook view of NMDA receptor calcium signals upended by new findings

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...
ジャパンタイムズ

Japanese researchers link COVID-19 ‘brain fog’ to neural receptors

People with post-COVID “brain fog” have unusually high numbers of a receptor that mediates neurotransmission in the central nervous system, Japanese researchers have found. According to a new study by ...
eLife

Molecular Architecture and Function Mechanism of Tri-heteromeric GluN1-N2-N3A NMDA Receptors

This important work advances our understanding of NMDAR diversity in the brain by providing evidence into the subunit arrangement, architecture, and activation mechanism of GluN1-N2-N3A tri-NMDAR.
Frontiers

Structure and gating of kainate receptors

Ionotropic glutamate receptors (iGluRs) are crucial for fast excitatory neurotransmission in the mammalian central nervous system (CNS). Kainate receptors (KARs), a subclass of iGluRs, are tetrameric, ...
Yahoo

Scientists Have Finally Uncovered What’s Behind Long COVID’s Most Taxing Symptom

"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." REMEMBER COVID? PLENTY of people have already moved past the lockdowns, social distancing, and other ...