The UAB researchers showed that TREM2 — which stands for triggering receptors expressed on myeloid cells 2 — is predominantly ...

A three-dimensional pharmacophore model for the binding of noncompetitive AMPA receptor antagonists was developed in order to map common structural features of highly active compounds. This hypothesis ...

Ligand-gated ion channels undergo conformational changes that transfer the energy of agonist binding to channel opening. Within ionotropic glutamate receptor (iGluR) subunits, this process is ...

Brain Receptor Structure Revealed to Support Cerebellum Function Repair June 23, 2025 Neurons [BlackJack3D / 1495440392 / E+] ...

Scientists have mapped the molecular structure of glutamate receptors in the cerebellum for the first time using cryo-electron microscopy.