AMPA Receptors On Cell Membrane Make Us Smarter Date: September 15, 2009 Source: NWO (Netherlands Organization for Scientific Research) Summary: AMPA receptors are an important regulating factor ...

This site, located outside the membrane electric field, ... GluA2-containing AMPA receptors form a continuum of Ca 2+-permeable channels, Nature (2025). DOI: 10.1038/s41586-025-08736-2.

These receptors are located mostly at excitatory synapses and, thereby, ... NMDA receptors mediate LTD by dephosphorylating AMPA receptors and removing them from the synaptic membrane by endocytosis.

Using the polyamine toxin philanthotoxin, which selectively blocks calcium-permeable AMPA receptors, we show that synaptic transmission onto single hippocampal interneurons occurs by afferent ...

Scientists have mapped the molecular structure of glutamate receptors in the cerebellum for the first time using cryo-electron microscopy.

AMPA receptors, a subtype of receptor for the neurotransmitter glutamate, ... So we are left to presume that AMPA receptors located actually within the synapse are, ...

Dr. Uwe Schulte, Dr. Jochen Schwenk, Prof. Dr. Bernd Fakler, and their team have elucidated the enormous spatial and temporal dynamics in protein composition of the AMPA-type glutamate receptors ...

The AMPA receptor plays a critical role for one of the brain's most abundant neurotransmitters -- glutamate -- which activates brain cells (neurons) ...

Specifically, the mechanisms by which loss of AMPA receptors leads to the loss of NMDA receptors remain unclear. There is undoubtedly a correlation between the two events because of their anatomical ...

As AMPA receptors are one of the most important molecules in neurotransmission, this method could potentially teach us a lot about the mechanisms of psychiatric disorders. Read the full story here .

“Because of the predominant hippocampal location of TARP-γ8-dependent AMPA receptors, we believe that the efficacy and side effect profile of CERC-611 may represent an improvement compared to ...

In the study, "GluA2-containing AMPA receptors form a continuum of Ca²⁺-permeable channels," published in Nature, ... This site, located outside the membrane electric field, ...