The crash near the Louisville Muhammad Ali International Airport marked the deadliest accident in UPS Airlines history.

Video of the deadly Louisville, Kentucky, crash showed flames on one of the plane's wings and a huge fireball erupting as the aircraft hit the ground.

A team of investigators arrived in Louisville, Kentucky, Wednesday to look into what led to the fiery crash of a UPS cargo plane shortly after it took off from the Louisville airport Tuesday, killing at least 12 people and destroying businesses and other structures in the area.

A federal government shutdown is causing a 10% reduction in flights at 40 major U.S. airports. Louisville Muhammad Ali International Airport is among the airports that will see flight reductions starting Friday.

The MD-11 that exploded spent much of September and October at ST Engineering at San Antonio International Airport. The company maintains the carrier's fleet.

We have viewed airport CCTV security coverage, which shows the left engine detaching from the wing during the takeoff roll,” National Transportation Safety Board (NTSB) Member Todd Inman said.

Video from a business just 500 feet away captured the fiery destruction when a UPS plane crashed after takeoff in Louisville, Kentucky.

LOCATION AND SCALEThe Worldport facility in Louisville Muhammad Ali International Airport spans about 5.2 million square feet, or roughly 90 football fields and serves as the global air logistics nerve center for UPS. Handles around 2 million packages per day. The automated sorting system can process up to 420,000 packages/letters per hour.