Since its discovery in the 1990s, "programmed cell death protein 1," or PD-1, has been regarded as a leading target in cancer treatments. A "checkpoint" receptor that often resides on the surface ...

Researchers have discovered that mouse PD-1 is significantly weaker than human PD-1, calling into question their reliability ...

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do ...

About LM-299 LM-299 is an investigational bispecific antibody targeting both programmed cell death protein-1 (PD-1) and vascular endothelial growth factor (VEGF). This innovative therapeutic ...

Table 1 In vivo and in vitro approaches to attenuate neurodegeneration in experimental models by targeting programmed cell death Full size table One of the few potential pharmacological approaches ...

Drugs that block cytotoxic T lymphocyte associated protein 4 (CTLA-4), programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) activate the cancer-killing T cells that had ...

For decades, we’ve believed the bright redness of sunburn — along with its irritating sting and peeling skin — was the result ...

This executive interview, sponsored by BeiGene, is with Jan-Henrik Terwey, Vice President, Medical Affairs Europe at BeiGene.

A novel molecular tool developed by a Lehigh University professor of biological sciences is enabling scientists to precisely ...

Spatial organization of proteins (dots) within a human cell: Each protein is placed according ... of proteins involved in a form of programmed cell death called ferroptosis led the researchers ...