Background Pulmonary hypertension (PH) is a progressive cardiopulmonary condition associated with increased morbidity and mortality. The extracellular matrix component hyaluronan (HA) is linked to ...

Introduction In Hong Kong, tuberculin skin test (TST) with a 15 mm cut-off was used at 0 and 3 months for contact screening, but half of future tuberculosis cases might be missed. Follow-on interferon ...

Background Owing to discrepancies in methodologies and how idiopathic pulmonary fibrosis (IPF) is diagnosed it is challenging to establish a consistent understanding of the disease burden In the UK, ...

The postnatal growth of the pre-acinar or conducting airways of the lung was examined by measuring the dimensions of selected axial pathways in lungs at different stages of development. The material ...

Introduction Identifying acute hypercapnic respiratory failure is crucial in the initial management of acute exacerbations of COPD. Guidelines recommend obtaining arterial blood samples but these are ...

Background Relapse continues to place significant burden on patients and tuberculosis (TB) programmes worldwide. We aimed to determine clinical and microbiological factors associated with relapse in ...

1 Royal Brompton & Harefield Hospitals, Guy’s and St.Thomas’ NHS Foundation Trust, London, UK Since the Guideline, there is deeper understanding of referral characteristics, outcome measures, patient ...

Introduction and objectives Airway sensory nerves involved in the cough reflex may be mediated by adenosine triphosphate (ATP) agonism of P2X purinoceptor 3 (P2X3) receptors. Transient receptor ...

BACKGROUND Varicella is 25 times more likely to be complicated by pneumonia in adults than in children. Data on changes in lung function following pneumonia are limited. This study was undertaken to ...

Introduction and objectives Malignant pleural mesothelioma (MPM) pathogenesis is strongly influenced by the tumour microenvironment, supporting a role for immune checkpoint inhibition as a therapy.

1 Centre for Occupational and Environmental Medicine, Rikshospitalet-Radiumhospitalet Medical Center, Oslo and Department of Respiratory Medicine, Faculty Division Rikshospitalet, University of Oslo, ...

Correspondence to Dr Serenydd Everden, Department of Respiratory Medicine, Royal Berkshire NHS Foundation Trust, Reading RG1 5AN, UK; serenydd.everden{at}googlemail.com A 57-year-old man with no ...