Background Owing to discrepancies in methodologies and how idiopathic pulmonary fibrosis (IPF) is diagnosed it is challenging to establish a consistent understanding of the disease burden In the UK, ...

Background Critical care medicine has historically relied on syndromic diagnoses such as sepsis, acute respiratory distress ...

Artificial intelligence (AI) is a branch of computer science developed in the 1950s to imitate the human ability for solving ...

Correspondence to Professor Claire L Shovlin, Professor of Practice (Clinical and Molecular Medicine), NHLI Vascular Science, Imperial College London, Imperial Centre for Translational and ...

Lung cancer is the commonest fatal malignancy worldwide in both men and women, accounting for >1.3 million deaths each year. The mean time from diagnosis to death is 18 months, new paradigms are ...

Background Acute respiratory distress syndrome (ARDS) is a rapidly evolving condition. Dynamic assessments using patient trajectories may provide novel insights into disease heterogeneity. The primary ...

Objectives Infliximab, an anti-TNF agent, is used to treat sarcoidosis that does not respond to corticosteroids or second-line agents. The efficacy of other anti-TNF agents, non-TNF biologics and ...

Introduction Current bronchiectasis guidelines advise against the use of inhaled corticosteroids (ICS) except in patients with associated asthma, allergic bronchopulmonary aspergillosis (ABPA) and/or ...

Introduction Combination of the noradrenergic atomoxetine with either the antimuscarinic aroxybutynin or trazodone has been shown to improve obstructive sleep apnoea (OSA) severity. However, ...

Introduction Tocilizumab improves outcomes in critically ill patients with COVID-19. Whether other immune-modulator strategies are equally effective or better is unknown. Methods We investigated ...

Correspondence to Dr Jeffrey H Barsuk, Division of Hospital Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 211 E. Ontario St, Suite 717, Chicago, IL 60611, USA; ...

The BTS/SIGN/NICE have recently published updated guidance for the treatment of asthma.1 The guideline advises that inhaler choice should be based on the lowest environmental impact among suitable ...