image image By reconstituting eukaryotic DNA replication in vitro, this study addresses the effects of physiological quadruplex secondary structures on genome stability. G‐quadruplexes (G4s) and ...

These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic ...

Ago2 differentially regulates oncogenic and tumor-suppressive miRNAs in cancer cells. This discrepancy suggests a secondary event regulating Ago2/miRNA action in a context-dependent manner. We show ...

After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...

The authors contacted the journal upon discovering a subpanel was incorrectly selected in Figure 6E. After discussions with the authors and conducting its own analysis, the journal corrects the ...

Although the Arabidopsis thaliana RPD3-type histone deacetylase HDA19 and its close homolog HDA6 participate in SIN3-type histone deacetylase complexes, they display distinct biological roles, with ...

imageimageTransposable elements contribute to evolution, but their own diversification remains incompletely understood. Here, insect endogenous retroviruses (iERVs) are shown to diversify through the ...

Stabilization of microtubule plus end-directed kinesin CENP-E at the metaphase kinetochores is important for chromosome alignment, but its mechanism remains unclear. Here, we show that CKAP5, a ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. When dormant naïve T cells first become ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

Aggressive prostate cancer (PCa) variants associated with androgen receptor signaling inhibitor (ARSI) resistance and metastasis remain poorly understood. Here, we identify the axon guidance ...