Hypoxia-inducible factor - Wikipedia
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia. [1][2] They also respond to instances of …
Redefining the role of hypoxia-inducible factors (HIFs) in oxygen ...
Mar 16, 2025 · We propose an alternative model focused on understanding the dynamics of HIFs’ activity within its physiological context. Our model suggests that HIFs would not respond to but …
Hypoxia Inducible Factor - an overview | ScienceDirect Topics
Hypoxia-inducible factor (HIF) is defined as a key transcription factor that mediates physiological responses to low oxygen levels by regulating the expression of genes involved in processes …
The Distinct Role of HIF-1α and HIF-2α in Hypoxia and ... - PubMed
May 4, 2025 · The current review highlights the different roles and regulatory mechanisms of HIF-1α and HIF-2α isoforms, focusing on their involvement in cell metabolism and the multi-step …
Hypoxia Inducible Factors (HIFs) - Bio-Techne
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreased oxygen level in the cellular environment. Various isoforms and splice variants have been identified and their …
Hypoxia Inducible Factors - Novus Biologicals
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreased oxygen level in the cellular environment. Various isoforms and splice variants have been identified and their …
The Distinct Role of HIF-1α and HIF-2α in Hypoxia and …
May 4, 2025 · The current review highlights the different roles and regulatory mechanisms of HIF-1α and HIF-2α isoforms, focusing on their involvement in cell metabolism and the multi-step …
HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, …
HIF1 protein identified as key trigger in common tendon diseases
12 hours ago · Complaints such as pain in the Achilles tendon, tennis elbow, swimmer's shoulder and jumper's knee are familiar to many young sportspeople, as well as to older individuals. …
Modulation of hypoxia-inducible factors (HIF) from an integrative ...
Hypoxia-inducible factors (HIFs) are transcription factors that respond to changes in available oxygen in the cellular environment and drives cellular adaptation to such conditions.